Chadwick's sign is noted in a pregnant client's record. Which hormone is responsible for this sign?

Chadwick's sign refers to the bluish discoloration of the vaginal mucosa and cervix observed during pregnancy, typically visible around six to eight weeks of gestation. This sign is primarily attributed to increased vascularity and blood flow to the pelvic region, which is significantly influenced by estrogen. Estrogen promotes the engorgement of blood vessels and increases blood circulation, resulting in this characteristic change.

In the context of pregnancy, the surge of estrogen levels contributes to many physiological changes, including those in the reproductive organs, and Chadwick's sign is one visible outcome of these changes. Thus, the correct identification of estrogen as the hormone responsible for this sign aligns well with its role in enhancing vascularity and promoting the overall adaptations necessary for sustaining pregnancy.